Anti-Inflammatory Pharmaceutical Intermediates Cetirizine hydrochloride CAS 83881-52-1
| Product name |
Cetirizine hydrochloride |
| CAS number |
83881-52-1 |
| Molecular formula |
C21H26Cl2N2O3 |
| Molecular weight |
425.35 |
| Appearance |
White Powder |
| Purity |
99.0% |
| Description |
Cetirizine is a potent H1 receptor antagonist that enters the body orally and rapidly binds to the histamine H1 receptor on the target cell membrane, blocking histamine from activating target cells. Cetirizine has no significant anticholinergic and anti-serotonin effects. At normal doses, it is not easy to penetrate the blood-brain barrier. This product can inhibit the histamine transmission in the initial stage of allergic reaction, reduce the migration activity of inflammatory cells and the release of transmitters in the late stage of allergic reaction, so it is also effective for allergic reactions in the late stage. This product is a highly selective H1 receptor antagonist, and has not been found to have adverse effects on cardiac electrical activity. |
| Function |
Cetirizine is indicated for respiratory, skin and ocular allergic diseases, including perennial allergic diseases such as allergic skin diseases, hives, allergic rhinitis, itchy eyes, conjunctivitis and asthma. This product is also used to treat various types of dermatological allergic diseases. Such as for chronic, artificial, cold, delayed stress, solar measles and atopic dermatitis. This product is also an effective drug for rapid whealing and rapid-onset nucleus and itching caused by mosquito bites. |
1. Cetirizine is mainly used for urticaria and skin itch caused by allergy ;
2. Cetirizine is used to treat tardive and pressure urticaria,can replace glucocorticoid to be as regular treatment but should be used a large amount;
3. Cetirizine can also have the function for cold urticaria.
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