Visanne ingredient Dienogest powder Dienogestrel CAS 65928-58-7
Physical Characters and specifications
| Product name |
Dienogestrel |
| CAS No. |
65928-58-7 |
| Molecular Formula |
C20H25NO2 |
| Molecular weight |
311.422 |
| EINECS NO. |
639-448-2 |
| Grade Standard |
Medicine Grade |
| COA |
Avaliable |
| Item |
Specifications |
| Appearance |
White Powder. |
| Purity |
99%min |
| Melting point |
210-214ºC |
| Specific rotation |
D25-290°(c=0.5 in pyr idine) |
| Boiling point |
451.46ºC |
| Density |
1.0899 |
| Refractive index |
1.5614 |
| Optical rotation |
[α]/D -305 to -325°, c = 1 in |
| Storage condition |
-20ºC |
| Shelf life |
2 years |
Product Introduction
Dienogest Powder is a progestin, or a synthetic progestogen. It is available in combination with estradiol valerate (as Natazia, Qlaira) or ethinylestradiol (as Valette) for use as an oral contraceptive, and by itself (as Visanne, Dinagest) for the treatment of endometriosis in Europe, Australia, and Japan. Although available in combination with estrogen as a contraceptive in the United States, dienogest is not available in this country by itself. In addition to its progestogenic effects, dienogest has antiandrogenic activity, and as a result can improve androgenic symptoms such as acne.
Function and Application
Dienogest is used primarily as a contraceptive in combination with ethinylestradiol. It is given as a tablet containing 2 mg of dienogest and 30 μg of ethinylestradiol. Dienogest is also available in a quadriphasic oral contraceptive pill combined with estradiol valerate, marketed as Natazia in the United States and Qlaira in some European countries and Russia. This formulation is also approved for the treatment of heavy menstrual bleeding.
Application
Dienogest. German Jenapharm company developed the contraceptive drug, due to its strong inhibition of ovulation and application in oral contraceptive. Dienogest is a mixture of progesterone, pharmacology and have the advantages of natural and synthetic progesterone.
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