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| Customized: | Customized |
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Name: L-Carnosine
Introduction:
1) L-Carnosine (beta-alanyl-L-histidine) is a dipeptide of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues.
2) L-Carnosine and carnitine were discovered by Russian chemist V.Gulevich.Researchers in Britain,South Korea,Russiaand other countries have shown that carnosine has a number of antioxidant properties that may be beneficial. Carnosine has been proven to scavenge reactive oxygen species (ROS) as well as alpha-beta unsaturatedaldehydes formed from peroxidation of cell membrane fatty acids during oxidative stress. Carnosine is also a zwitterion, a neutral molecule with a positive and negative end.
3)Like carnitine, carnosine is composed of the root word carn, meaning flesh, alluding to its prevalence in animal protein. A vegetarian (especially vegan) diet is deficient in adequate carnosine, compared to levels found in a standard diet.
Carnosine can chelate divalent metal ions.
4)L- Carnosine can increase the Hayflick limit in human fibroblasts,as well as appearing to reduce the telomere shortening rate. Carnosine is also considered as a geroprotector.
Functions
L-Carnosine (L-Carnosine) is a dipeptide (two amino acids) often found in organs and tissues such as the brain, heart, skin, muscle, kidney and stomach. L-carnosine can activate human cells and anti-aging through two mechanisms: inhibit glycation and protect our cells from free radical damage. The consequence of glycation is that the cross-linking of sugar molecules and proteins will be uncontrolled (sugar molecules will stick In protein), loss of cell function and incomplete gene combination will accelerate aging. L-Carnosine (L-Carnosine) can also stabilize cell membranes and reduce brain lipid peroxidation, thereby preventing nerve and brain degeneration.
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