Customization: | Available |
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CAS No.: | 158563-45-2 |
Formula: | C61h87n15o9s |
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Product name | Nonapeptide-1 |
CAS No. | 158563-45-2 |
MF | C61H87N15O9S |
MW | 1206.5 |
Melting point | N/A |
Boiling point | N/A |
Density | 1.38±0.1 g/cm3(Predicted) |
Storage | N/A |
Nonapeptide-1 can prevent melanin synthesis and unwanted pigmentation by preventing activation of the tyrosinase, thus allowing for a better control over skin tone.
3. Product Mechanism
Binding of a-MSH to the MC1-Receptor on melanocytes is the first step in melanogenesis and the pigment formation. By binding and blocking the MC1-R, we can block the intracellular melanogenesis pathway and decrease the synthesis or the over expression of melanin produced by melanocytes.
Nonapeptide-1 an oligopeptide with an high affinity for MC1-R. It is a biomimetic peptide antagonist specific of the a-MSH (Alpha Melanocyte Stimulating Hormone). As an antagonist, it competes against the natural ligand (a-MSH) on its specific receptor (MC1-R) by preventing any further activation of the tyrosinase, and thus blocking melanin synthesis. Tyrosinase inhibition reduces the formation of unwanted pigmentation allowing for the control over skin tone and brown spots.
Nonapeptide-1 blocks the melanogenesis pathway and inhibits tyrosinase activity and melanin synthesis.
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