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Name: Finasteride
English synonyms: (5alpha,17beta)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
CAS Number: 98319-26-7
Molecular formula: C23H36N2O2
Molecular weight: 372.54
EINECS number: 620-534-3
Finasteride is for the treatment of hair loss in men. Finasteride belongs to a class of drugs known as 5-alpha-reductase inhibitors. It works by preventing test from breaking down into DHT, the hormone that is thought to cause male pattern baldness.
Additionally, it is registered in many countries for androgenetic alopecia (male-pattern baldness).
Benign prostatic hyperplasia
Physicians use finasteride for the treatment of BPH, informally known as an enlarged prostate. The dose is 5 mg once a day. Six months or more of treatment with finasteride may be required to determine the therapeutic results of treatment. If the drug is discontinued, any therapeutic benefits reverse within about -8 months. Finasteride may improve the symptoms associated with BPH such as difficulty urinating, getting up during the night to urinate, hesitation at the start of urination, and decreased urinary flow.
Male pattern baldness
Finasteride is used to treat male pattern hair loss (androgenetic alopecia) in men only. Treatment provides about 30% improvement in hair loss after six months of treatment, and effectiveness only persists as long as the drug is taken.
Off-label uses
Finasteride is sometimes used in hormone replacement therapy for male-to-female transsexuals in combination with a form of estrogen due to its antiandrogen properties. However, little clinical research of finasteride use for this purpose has been conducted and evidence of efficacy is limited.
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