Food Additive High Purity Konjac Glucomannan KGM glucomannan powder CAS. 11078-31-2
Glucomannan is a natural plant neutral polysaccharide formed by the polymerization of glucose and mannose through β-1,4 glycosidic bonds. It is also an excellent water-soluble dietary fiber. It belongs to edible hemicellulose and has unique physical and chemical properties. nature. Glucomannan mainly comes from the tubers of konjac, so it is also called konjac glucomannan (KGM for short). It has good plasticity, water absorption, film-forming, thickening, water retention and other physical and chemical properties biological properties. Glucomannan has very high medicinal value and edible value, and has small toxic and side effects.
1. The effect of KGM on glucose metabolism
Konjac food is an ideal food for diabetics, which has the effect of lowering blood sugar, improving symptoms and controlling the disease. In patients with type 2 diabetes treated with compound konjac granules, it was found that the decrease rate of fasting blood glucose was 53%, the decrease rate of 2 h postprandial blood glucose was 51%, and the decrease rate of glycated hemoglobin was 59.9%.
2. The effect of KGM on lipid metabolism
KGM affects lipid metabolism and has obvious hypolipidemic effect. In addition to lowering serum cholesterol in rats, konjac also has the effect of reversing fatty liver. In addition to good blood lipid lowering and obvious anti-fatty liver effects, konjac powder has no adverse effects on the absorption and utilization of Ca, Fe, Zn, and Cu.
3. The weight loss effect of KGM
KGM is a low-calorie diet food with obvious weight loss effect.
4. The effect of KGM on anti-cancer and immune function
Konjac refined powder can inhibit and prevent lung cancer in mice induced by p-methylnitronitrosoguanidine (MNNG). The number of animals with induced cancer and precancerous lesions was greatly reduced, and malignant tumors were reduced in the proportion of tumor types. Konjac powder can obviously promote the immune function of mice, increase the thymus index and spleen index, and inhibit the synthesis and release of interleukin-1 (IL-1), tumor necrosis factor-α (TNF-α) by macrophages (M ). TNF-α) has a significant promoting effect. In addition, mice also have a certain promoting effect on the level of TNF-α in serum. Therefore, KGM is expected to be used as an immunomodulatory auxiliary product for the treatment of tumors. In addition, KGM was also found to have inhibitory effects on spontaneous liver cancer, β-galactosamine-induced liver injury in mice, and colon cancer.
5. The effect of KGM on intestinal function
Konjac food can increase the average daily fecal wet weight and fecal water content, and can shorten the intestinal transit time and the average defecation time.
6. The effect of KGM on cellular aging
Long-term consumption of konjac powder can prolong the aging process of brain glial cells, cardiomyocytes and intimal endothelial cells of large and medium arteries, prevent atherosclerosis, and improve cardiovascular and vascular functions.
7. The effect of KGM on the absorption of trace elements
KGM had no effect on the excretion of Ca, Fe, Zn and Cu in the feces, serum and femur contents of rats. Human trials have not seen any effect on the absorption of Zn, Fe, and Ca. There were no significant changes in serum calcium and phosphorus content, femoral bone weight, bone calcium and phosphorus content, and bone morphometric parameters in KGM-fed rats, and no adverse effects on calcium and phosphorus metabolism and femoral calcium content were found.
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