Anti-Hair Loss 99% pure Minoxidil Setipiprant CB-03-01 RU58841 powder CAS 38304-91-5
Physical Characters and specifications
| Product name |
Minoxidil |
| CAS No. |
38304-91-5 |
| Molecular Formula |
C9H15N5O |
| Molecular weight |
209.25 |
| EINECS NO. |
253-874-2 |
| Grade Standard |
Medicine Grade |
| COA |
Please contact with Senwayer freely |
| Item |
Specifications |
| Appearance |
White or almost white crystalline powder. |
| Purity |
99%min |
| Melting point |
272-274ºC |
| Boiling point |
348.61ºC |
| Density |
1.1651 |
| Refractive index |
1.7610 |
| Flash point |
166.5±28.7ºC |
| Acidity coefficient (pKa) |
4.61(at 25ºC) |
| Solubility |
Slightly soluble in water, soluble in meth anol and in propy lene glycol. |
| Storage condition |
-20ºC |
| Shelf life |
3 years |
Product Introduction
Minoxidil was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure, with side effects that included hair growth and reversal of male baldness.Since the 1990s, numerous generic forms of minoxidil have become available to treat hair loss while the oral form is still used to treat high blood pressure.
Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. It is available over the counter for treatment of androgenic alopecia, among other baldness treatments, but measurable changes disappear within months after discontinuation of treatment. Its effectiveness has largely been demonstrated in younger men (18 to 41 years of age), the younger the better.
Minoxidil is a potassium channel agonist. It contains the chemical structure of nit ric oxide), a blood vessel dilator, and may be a nit ric oxide agonist. This appears to explain its vasodilatory effects, but may also be linked to minoxidil's ability to stimulate hair growth and treat hair loss. Since minoxidil is a ni tric oxide-related compound, it was suspected to act via activation of guanylate cyclase, an enzyme involved in vasodilation.
Function
Minoxidil
1. Minoxidil powder needs to be applied once or twice daily for hair to be maintained.
2. For maximum effect, the solution should be in contact with the scalp for hours before being washed out. It does not seem capable of reducing DHT or the enzyme responsible for its accumulation around the hair follicle, 5-aliha reductase, which are the main causes of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT already accumlated around the follicle has its expected effect, and the follicle usually shrinks again and eventually dies.
3.Minoxidil powder can promote hair regrowth,slow or stop hair loss and treat high blood pressure.
RU58841
RU58841 is the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of RU58841have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery.
Setipiprant
Setipiprant is the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of Setipiprant have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery.
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