Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Hormone High Quality 2-METHOXYESTRADIOL Powder CAS.362-07-2 99% Purity
Product name | 2-METHOXYESTRADIOL |
CAS no. | 362-07-2 |
Molecular Formula | C19H26O3 |
Molecular Weight | 302.41 |
Brand Name | Senwayer |
2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). It is derived from estrogen, although it binds poorly to known estrogen receptors, and belongs to the family of drugs called angiogenesis inhibitors. It has undergone Phase 1 clinical trials against breast cancers. Preclinical models also suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis. The CAS name for 2ME2 is (17 beta)-2-methoxyestra-1, 3, 5(10)-triene-3, 17-diol. It also acts as a vasodilator.
2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol. As an experimental drug candidate, it is being developed under the tradename of Panzem. It prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis), hence it is an angiogenesis inhibitor.