| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
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| Product name | 9-Methyl-9H-beta-carboline |
| CAS number | 2521-07-5 |
| Molecular formula | C12H10N2 |
| Molecular weight | 182.22 |
| Melting point | 105.0 to 109.0 °C |
| Boiling point | 367.3±24.0 °C(Predicted) |
| Density | 1.17±0.1 g/cm3(Predicted) |
| Appearance | Powder |
| Purity | 99.0% |
| Function | 9-Methyl-9H-beta-carboline promote the axonal development and neuronal regeneration of brain neurons in parkinson's patients, reduce the DNA damage under uv irradiation, and at the same time have the functions of refreshing the brain and adjusting sleep. |
| Discribe | Tumor is a new organism formed by abnormal proliferation of monoclonal cells due to the loss of regulation of growth in gene level by the cells of local tissue under the action of various tumor causing factors. In the world, tumor seriously endangers human health, affects human quality of life, and becomes one of the most important causes of death. One of the important sources of new anti-tumor drugs of natural products. β- Carboline is an anti-tumor compound isolated from Camellia, which kills tumor cells in the form of cytotoxic. This way of action makes β- Carboline has a high toxicity. modification β- The structure of carboline is in order to reduce toxicity and improve the antitumor activity, which attracts extensive research interest. stay β- The inventor of carboline structural modification β- The 3-position of carboline is introduced into carboxyl group and further coupled with benzyl amino acid to form β- Benzyl ester of 3-formyl amino acid of carboline can be reduced initially β- The aim of low toxicity of carboline and the improvement of anti-tumor activity. The inventors further realized that β- The 9-position of 3-formyl-amino acid benzyl ester of carboline and 9-methoxymethyl can be further reduced β- The aim of low toxicity of carboline and the improvement of anti-tumor activity. Based on the inventor's understanding, the inventor proposed 16 kinds of 9-methoxymethyl - β- Invention of benzyl carboline-3-formyl amino acid. The inventor's understanding just mentioned makes the invention show two outstanding creativity compared with the invention mentioned before: 1) the function of killing tumor cells by cytotoxic method disappears; 2) the activity of inhibiting tumor growth is greatly improved. |
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