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Name: Tranexamic acid
English synonyms: cyclocapron
CAS Number: 1197-18-8
Molecular formula: C8H15NO2
Molecular weight: 157.21
EINECS number: 214-818-2
Melting point: >300°C(lit.)
Boiling point: 281.88°C(rough estimate)
Density: 1.0806(rough estimate)
Refractive index: 1.4186(estimate)
Storage conditions: 2-8°C
Solubility: Freely soluble in water and in glacialacetic acid, practically insoluble in ethanol(96percent).
Form: Crystalline Powder
Acidity coefficient (pKa): pKa4.3(Uncertain); 10.6(Uncertain)
Color: White
Water solubility: 1g/6ml
Tranexamic acid is a synthetic derivative of lysine and belongs to an antifibrinolytic drug with hemostatic properties. Tranexamic acid can strongly adsorb to the lysine binding site (LBS) of the fibrin affinity site on plasmin and plasminogen, inhibiting the binding of plasmin, plasminogen and fibrin, thereby It strongly inhibits fibrinolysis caused by plasmin; in addition, in the presence of anti-plasmin such as macroglobulin in the serum, the anti-fibrinolytic effect of tranexamic acid is more obvious. Its bioavailability is 34%, and its half-life is 3.1h.