Factory Supply Quality Pure Mirtazapine Powder CAS 85650-52-8

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: 85650-52-8
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Color: White
• Name: Mirtazapine
• CAS: 85650-52-8
• Stock: Avaiable
• Sample: Avaiable
• Shelf Time: 3years
• Transport Package: Foli Bag
• Specification: 1KG
• Trademark: Senwayer
• Origin: China
• HS Code: 2902600000
• Production Capacity: 5000kg Per Year

Product Description

Factory supply quality pure Mirtazapine  powder CAS 85650-52-8regabalin
Product Name: Mirtazapine
CAS NO.: 85650-52-8
Molecular Formula: C17H19N3
Molecular Weight: 265.35
Purity: 99%
Appearance: White Powder
Grade: Pharmaceutical Grade

Introduction:

Mirtazapine (brand names: Avanza, Axit, Calixta, Mirtaz, Mirtazon, Remeron, Zispin) is an atypical antidepressant with noradrenergic and specific serotonergic activity. It blocks the α₂ adrenergic auto- and heteroreceptors (enhancing serotonin release), and selectively antagonizes the 5-HT₂ serotonin receptors in the central and peripheral nervous system. It also enhances serotonin neurotransmission at the 5-HT₁ receptor and blocks the histaminergic (H₁) and muscarinic receptors. Mirtazapine is not a serotonin or norepinephrine reuptake inhibitor but may increase serotonin and norepinephrine by other mechanisms of action.

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA) introduced by Organon International in the United States in 1996, and is used primarily in the treatment of depression. It is also commonly used as an anxiolytic, hypnotic, antiemetic and appetite stimulant. In structure, mirtazapine can also be classified as a tetracyclic antidepressant (TeCA) and is the 6-aza analogue of mianserin. It is also racemic-occurs as a combination of both (R)-(−)- and (S)-(+)-stereoisomers, both of which are active.

Application:
Mirtazapine is used to treat depression. Mirtazapine is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain to maintain mental balance.

Items	Standard	Result
Appearance	White or off-white powder	Complies
Identification	The IR absorption spectrum is accordant with the spectrum obtained with CRS	Complies
Solubility	, Practically insoluble in water,freely soluble in anhydrous ethanol	Complies
specific rotation	-0.10°~+0.10° (anhydrous substance)	+0.001°
Water	≤3.5%	2.8%
Sulfated ash	≤0.10%	0.04%
granularity	80%<75 m	39.28 m
Residual solvents	Ethanol ≤5000ppm	130ppm
Impurity	Impurity A A≤0.10%	ND
	Impurity B B≤0.10%	ND
	Impurity C C≤0.10%	ND
	Impurity D D≤0.10%	ND
	Impurity E E≤0.10%	ND
	Impurity F F≤0.10%	ND
	Individual impurity ≤0.10%	ND
	Total impurities ≤0.20%	ND
Microbial limit test	aerobic bacteria≤1000CFU/g	<10CFU/g
	fungus≤1000CFU/g	<10CFU/g
	Absence of escherichia coli	ND
Assay	99.0~101.0%(anhydrous substance)	100.0%
Conclusion	Complies to EP7.0

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