Hot Selling Pharmaceutical Grade Phentolamine Powder with Best Price CAS 50-60-2

• Customization: Available
• Product Name: Phentolamine
• CAS No.: 50-60-2
• Model NO.: Phentolamine
• Molecular Formula: C17h19n3o
• Molecular Weight: 281.35
• Melting Point: 174-175°
• Boiling Point: 424.02°c (Rough Estimate)
• Density: 1.0510 (Rough Estimate)
• Transport Package: Foil Bag
• Specification: 1kg /bag
• Trademark: SENWAYER
• Origin: China
• HS Code: 29335990
• Production Capacity: 1000kg/Month

Product Description

 Hot Selling Pharmaceutical Grade Phentolamine Powder with Best Price CAS 50-60-2

Product name	Phentolamine
CAS number	50-60-2
Molecular formula	C17H19N3O
Molecular weight	281.35

Appearance	White Powder
Purity	99.0%
Description	Phentolamine is used in the diagnosis of vasospasm diseases, such as acral arterial spasm (i.e. Raynaud's disease), cyanosis of hands and feet, septic toxic shock and pheochromocytoma. It is also effective for ventricular premature beats.

 

Phentolamine is competitive and non selective α 1 and α 2 receptor blocker, its action duration is short. By blocking the cell process junction α 1 and α 2 receptor, which causes vasodilation and reduction of blood pressure, mainly arterioles, followed by veins. As a result, the resistance of systemic circulation and pulmonary circulation and arterial pressure are reduced; Through block α 2 receptor, which can increase the release of noradrenaline from the upper gland, resulting in increased myocardial contractility and tachycardia. Phentolamine also reduced renal perfusion pressure and caused * retention of sodium. It can also antagonize the vasoconstrictive response induced by noradrenaline and a drenaline. Due to the pre junction of cell process α The blocking effect of 1 receptor leads to the increase of the release of noradrenergic hormone from neurons. Phentolamine can enhance the contractility and rate of myocardium. After intravenous administration, the systemic mean arterial pressure and systemic vascular resistance can be temporarily reduced.



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