Amino acid 4-Aminobutyric acid / GABA powder CAS 56-12-2
| Product Name |
4-Aminobutyric acid / GABA |
| CAS No. |
56-12-2 |
| Molecular formula |
C4H9NO2 |
| Molecular weight |
103.12 |
| Purity |
98% |
Gamma-aminobutyric acid (GABA) is a natural active ingredient widely distributed in animals and plants. The seeds, rhizomes and tissue fluids of plants such as legumes, ginseng, and Chinese herbal medicines all contain γ-aminobutyric acid. In animals, γ-aminobutyric acid is almost exclusively found in nerve tissues, and the content in brain tissue is about 0.1 to 0.6 mg/g tissue. Immunological studies have shown that the highest concentration of γ-aminobutyric acid is the substantia nigra of the brain.
γ-aminobutyric acid is a strong neurosuppressive amino acid, which has the physiological effects of sedation, hypnosis, anticonvulsant, and lower blood pressure. It is an inhibitory neurotransmitter (Inhibitory Neurotransmitter), which can inhibit animal activity and reduce energy consumption. GABA acts on the γ-aminobutyric acid receptor in animal cells. The γ-aminobutyric acid receptor is a chloride ion channel. The inhibitory or excitability of γ-aminobutyric acid depends on the chloride ion concentration inside and outside the cell membrane. Yes, when the γ-aminobutyric acid receptor is activated, the chloride channel is opened, which can increase the permeability of the cell membrane to chloride ions, so that the chloride ions can flow into the nerve cells, cause the cell membrane to hyperpolarize, and inhibit the activation of nerve cells. Reduce the amount of animal exercise.
It reduces energy consumption by reducing the unconscious movement of animals, thereby achieving the purpose of promoting growth. γ-aminobutyric acid can promote the secretion of animal gastric juice , thereby increasing the growth rate and feed intake; it can excite the feeding center of the animal, thereby increasing the feed intake. It is a kind of neurosuppressive product.
1. GABA is widely distributed in plants and animals, such as seeds, rhizomes and tissue fluids of legumes, ginseng, and Chinese herbal medicines. In animals, GABA almost only exists in nerve tissue fluid, and the content in brain tissue is about 0.1-0.6 mg/g tissue;
2. Apply microbial technology to ferment to produce GABA by screening high-quality and high-yielding safe strains;
3. GABA, known as "emotional vitamin", is an extremely important staherb neurotransmitter, which can effectively regulate brain waves, supplement sufficient GABA, and have significant effects in improving insomnia, depression and menopausal syndrome.
(1) Calm nerves and anti-anxiety.
Medical scientists have proven that γ-aminobutyric acid is an inhibitory transmitter of the central nervous system and one of the most important neurotransmitters in brain tissue. Its role is to reduce neuronal activity and prevent nerve cells from overheating. γ-aminobutyric acid can bind to and activate anti-anxiety brain receptors, and then work in concert with other substances to prevent anxiety-related information from reaching the brain indicating center.
(2) Lower blood pressure.
Gamma-aminobutyric acid can act on the vascular movement center of the spinal cord, effectively promote vasodilation, and achieve the purpose of lowering blood pressure. According to reports, the effective antihypertensive component of Chinese medicine such as astragalus is γ-aminobutyric acid.
(3) Treat diseases.
In 1997, Seitaro Daikuma's research showed that γ-aminobutyric acid is related to the formation of certain diseases. The concentration of γ-aminobutyric acid in the spinal cord of patients with Parkinson's disease is low, and the concentration of γ-aminobutyric acid in the spinal fluid of patients with epilepsy It is also lower than normal. Research conducted by Osaka University School of Medicine in Japan shows that γ-aminobutyric acid has a significant improvement effect on Kupperman's syndrome. In addition, the decrease of γ-aminobutyric acid in nerve tissue is also related to the formation of neurasthenia such as Huntington disease and Alzheimer's disease.
(4) Promote ethanol metabolism.
Taking alcoholics as subjects, taking γ-aminobutyric acid and drinking 60ml of whiskey, blood was collected to determine the concentration of ethanol in the blood, and it was found that the concentration of the latter was significantly lower than that of the control group.
(5) Others.
The latest research shows that γ-aminobutyric acid also has the functions of preventing skin aging, eliminating body odor, improving lipid metabolism, preventing arteriosclerosis, and effectively losing weight.
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