• Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
  • Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
  • Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
  • Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
  • Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
  • Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5

Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5

Powder: Yes
Customized: Customized
Certification: GMP, HSE, ISO 9001, USP, BP
Suitable for: Elderly, Children, Adult
State: Solid
Purity: >99%
Samples:
US$ 100/Piece 1 Piece(Min.Order)
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Customization:
Diamond Member Since 2019

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Rating: 5.0/5
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Basic Info.

Model NO.
2521-07-5
Other Name
9-Me-Bc
CAS
2521-07-5
Mf
C12h10n2
MW
182.22
Einecs
/
Sample
Available
Usage
Nootropics Product
Transport Package
Bottle, Can, Drum, Plastic Container, Vacuum Packe
Specification
Powder
Trademark
Senwayer
Origin
Wuhan, China
HS Code
3001200010
Production Capacity
1000 PCS Per Month

Product Description

Pharmaceutical API Nootropics High Purity 9-Methyl-9H-beta-carboline CAS 2521-07-5
Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5

Name: 9-Methyl-9H-beta-carboline
English synonyms: 9-Me-BC
CAS Number: 2521-07-5
Molecular formula: C12H10N2
Molecular weight: 182.22

Melting point: 105.0to109.0°C
Boiling point: 367.3±24.0°C(Predicted)
Density: 1.17±0.1g/cm3(Predicted)
Acidity coefficient (pKa): 8.21±0.30(Predicted)

9-Methyl-β-carbolines appear to induce DNA damage when exposed to ultra-violet light.

In vitro studies with dopaminergic neuron cell cultures demonstrated increased expression of tyrosine hydroxylase and associated transcription factors, increased neurite outgrowth, regeneration of neurons after chronic rotenone administration, and reduced expression of inflammatory cytokines. In studies of primary mesencephalic dopaminergic neuron cell cultures, the substance increased the number of differentiated dopaminergic neurons and produced higher levels of transcription factors associated with dopaminergic differentiation.9-Me-BC also inhibited the oxidation of the neurotoxin precursor MPTP to the dopaminergic neurotoxin MPP+ in vitro.

Rodent studies in vivo demonstrated elevated hippocampal dopamine levels, improved spatial learning performance in a radial maze test, and increased dendrite outgrowth in the dentate gyrus of the hippocampus,as well as restoration of the number of tyrosine hydroxylase expressing neurons in the left striatum after an injection of MPP+ had reduced the number of such cells by 50% in an animal model of Parkinsonism.

9-Me-BC is a known inhibitor of monoamine oxidase A and monoamine oxidase B, and has been proposed for further investigation in the treatment of Parkinson's disease.

It may also possess photosensitizing effects.

Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5

Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5


 


Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5
Pharmaceutical API Nootropics High Purity 9-Methyl-9h-Beta-Carboline CAS 2521-07-5

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