Supply Pure Fluoxetine HCl Power CAS 56296-78-7 Antidepressant Drug Fluoxetine Hydrochloride

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: Fluoxetine hcl
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Color: White
• Name: Fluoxetine
• CAS: 56296-78-7
• Stock: Avaiable
• Sample: Avaiable
• Shelf Time: 3years
• Transport Package: Foli Bag
• Specification: 1KG
• Trademark: Senwayer
• Origin: China
• HS Code: 2902600000
• Production Capacity: 5000kg Per Year

Product Description

supply pure Fluoxetine hcl power CAS 56296-78-7 Antidepressant Drug Fluoxetine Hydrochloride

Products Name: Fluoxetine hydrochloride

Synonyms : Methyl[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amine hydrochloride; N-Methyl-gama-[4-(trifluoromethyl)

CAS No: 59333-67-4;56296-78-7

EINECS No: 260-101-2

Molecular Formula: C23H23NO4

Molecular Weight: 377.433

Description 

Fluoxetine was shown to be effective for depression in six-week-long double-blind controlled trials, where it also alleviated anxiety and improved sleep. Fluoxetine was better than placebo for the prevention of depression recurrence when the patients, who originally responded to fluoxetine, were treated for a further 38 weeks. Efficacy of fluoxetine for geriatric, as well as pediatric, depression was also demonstrated in placebo-controlled trials.

Research suggests that a significant part of the resistance to the SSRIs paroxetine (Paxil) and citalopram(Celexa) can be explained by the genetic variation of Pgp transporter. Paroxetine and citalopram, which are Pgp substrates, are actively transported from the brain by this protein. Fluoxetine is not a substrate of Pgp, and thus a switch from paroxetine or citalopram to fluoxetine may be beneficial to the nonresponders

Appearance	White crystal	White crystal
Identification A:Infrared absorption B:Retention of time	A: Positive B: Positive	A: Complies B: Complies
Assay	98.0~101.5%	100.20%
Optical rotation	-0.05~+0.05	+0.01
Total impurity	≤0.5%	Complies%
3-methylaminol-l-phenylpropan-l-ol	≤0.25%	0.05%
N-methyl-3-phenylpropyl-l-amine	≤0.25%	0.05%
N-methyl-3-phenyl-3-(trifluoromet hylphenoxy)   propyl-l-amine	≤0.15%	0.03%
Other impurity	≤0.10%	Complies
Organic volatile impurity	Complies	Complies
Sulphated ash	≤0.1%	0.02%
Water	≤0.5%	0.20%
pH	4.5~6.5	5.70
Heavy metals	≤10ppm	Complies
Solubility	Colorless clear	Colorless clear
TVC	≤10 cfn/g	Complies
Mould and yeast	≤10 cfn/g	Complies
Conclusion: comply with the USP30/BP2002

Application
Fluoxetine is frequently used to treat major depression, obsessive compulsive disorder, bulimia nervosa,panic disorder, body dysmorphic disorder, premenstrual dysphoric disorder, and trichotillomania. Caution should be taken when using any SSRI for bipolar disorder as this can increase the likelihood of mania; however, fluoxetine can be used with an antipsychotic (such as quetiapine) for bipolar. It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.

Dosage:
20mg each time, 1 times, every morning to take, if after a few weeks the curative effect is not obvious to 20mg each time, two times a day (early, late each time), but the daily dosage of not more than 80mg