Customization: | Available |
---|---|
CAS No.: | 1968-05-4 |
Formula: | C17h14n2 |
Still deciding? Get samples of US$ 95/kg
Request Sample
|
Suppliers with verified business licenses
Audited by an independent third-party inspection agency
Product name | 3,3'-Diindolylmethane |
CAS No. | 1968-05-4 |
MF | C17H14N2 |
MW | 246.31 |
Melting point | 167 °C |
Boiling point | 230 °C(Press: 0.01 Torr) |
Density | 1.271±0.06 g/cm3(Predicted) |
Storage | 2-8°C |
Diindolylmethane is a phytonutrient and plant indole found in cruciferous vegetables including broccoli, Brussels sprouts, cabbage, cauliflower and kale, with potential anti-androgenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial estrogen metabolism in both sexes by reducing the levels of 16-hydroxy estrogen metabolites and increasing the formation of 2-hydroxy estrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown.
3. Product Benefits
As a partial CB2 agonist, DIM may help with neuroinflammation by working on the endocannabinoid system.
DIM can also protect against inflammation by acting on GPR84.
DIM also has potent COX-2 inhibition properties.
DIM is potent at fighting cancer.
For example, DIM inhibited the growth of mammary gland cell cancer, (via modulation of estrogen receptor α and AhR).
Through the activation of Aryl Hydrocarbon Receptors (AhR) and Nrf2 signaling pathways, DIM effectively increases detoxification and reduces inflammatory signaling
4. Product Side Effects
When taken by mouth: Diindolylmethane is commonly consumed in foods. A typical diet supplies 2-24 mg of diindolylmethane daily. It is possibly safe for most people when taken in doses up to 150 mg daily for up to 1 year. The most common side effects include headache, nausea, vomiting, gas, and diarrhea.
Taking larger doses of diindolylmethane is possibly unsafe. Taking 600 mg of diindolylmethane daily might lower sodium levels in some people.
FAQ
Our Product purity and quality is guaranteed by lab test for each batch