| Type: | Pharmaceutical Intermediates |
|---|---|
| Appearance: | Powder |
| Quality: | Refined |
| Colour: | White |
| Types: | Raw Powder |
| Storage: | Sealed in Dry Room |
| Customization: |
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Audited Supplier 
GTS-21 dihydrochloride is a selective α7 nicotinic acetylcholine receptor agonist, has recently been established as a promising treatment for inflammation. Target: nAChRin vitro: GTS-21 is one of the most potent α7nAChR agonists, has been reported to attenuate pro-inflammatory cytokine production, improve outcomes in sepsis models, pancreatitis, and ischemia-reperfusion injury, and inhibit the production of endotoxin-induced TNF in lung tissue. In addition, recent studies have demonstrated that GTS-21 inhibits the activities of endothelial cells and monocyte macrophages, as well as the secretion of pro-inflammatory cytokines in peripheral blood samples, by regulating the JAK2-STAT3 pathway. [1] in vivo: In septic animals, GTS-21 significantly ameliorated GI motility, lowered systemic and colonic levels of IL-6, decreased colonic permeability, and decreased the number of positive cultures obtained from blood and mesenteric lymph nodes. Splenectomy prevented animals from developing sepsis-induced ileus. Chrna7 mice displayed a more severe septic phenotype, whereas GTS-21 remarkably was also beneficial in these animals...
Function of GTS-21
Nootropics also referred to as smart drugs, memory enhancers, neuro enhancers, cognitive enhancers, and intelligence enhancers, are drugs, supplements, nutraceuticals, and functional foods that purportedly improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration. Nootropics are thought to work by altering the availability of the brain's supply of neurochemicals (neurotransmitters, enzymes, andhormones), by improving the brain's oxygen supply, or by stimulating nerve growth...
Application of GTS-21
GTS-21 has a high affinity for the rodent α7nAChR but its affinity for human α7nAChR is described to be low. Its metabolite, 4OH-(GTS-21) has been described to be a selective partial agonist with greater efficacy for both human and rat α7nAChRs (Conejero-Goldberg et al., 2008, Kem, 2000).
Both GTS-21 itself and its demethylated active metabolite 4-OH-GTS-21[3] display nootropic[4] and neuroprotective effects, and GTS-21 is being investigated for the treatment of Alzheimer's disease,nicotine dependence,and, most significantly, for schizophrenia ..
| Name | CAS No. | Purity |
| Magnesium Taurate | 334824-43-0 | 98.0% |
| Galantamine Hydrobromide | 69353-21-5 | 98.0% |
| Tianeptine | 66981-73-5 | 99.0% |
| Tianeptine sodium | 30123-17-2 | 99.0% |
| Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99.0% |
| 9-ME-BC(9-Methyl-9H-beta-carboline) | 2521/7/5 | 99.0% |
| Agomelatine | 138112-76-2 | 99.0% |
| 6-Paradol 98% | 27113-22-0 | 98% Oil form |
| 6-Paradol 50% | 27113-22-0 | 50% Powder form |
| Nicotinamide Riboside Chloride(NRC) | 23111-00-4 | 98.0% |
| Beta-Nicotinamide Mononucleotide(NMN) | 1094-61-7 | 98.0% |
| β-Nicotinamide Adenine Dinucleotide(NAD+) | 53-84-9 | 98.0% |
| Noopept,GVS-111 | 157115-85-0 | 99.0% |
| Piracetam | 7491-74-9 | 99.0% |
| Phenibut | 1078-21-3 | 99.0% |
| Coluracetam | 135463-81-9 | 99.0% |
| N-Methyl-D-aspartic acid(NMDA) | 6384-92-5 | 99.0% |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 99% Powder form |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 50% Graininess form |
| Citicoline | 987-78-0 | 99.0% |
| PRL-8-53 | 51352-87-5 | 98.0% |
| NSI-189 Phosphate | 1270138-41-4 | 99.0% |
| Fonturace.tam hydrazide | 77472-71-0 | 99.0% |
| N-Acetyl-L-cysteine ethyl ester | 59587-09-6 | 98.0% |
| 1-(1-Adamantylcarbonyl) proline | 35084-48-1 | 98.0% |
| YK-11 | 431579-34-9 | 99.0% |
| TLB-150 | 1208070-53-4 | 99.0% |
| OTR-AC | 99.0% | |
| 5a-hydroxy laxogenin | 56786-63-1 | 99.0% |
FAQ
Q1:Can i get free sample ?
A: Yes, most product we can send you small free sample, you just need to pay the shipping cost .
Q2:Which payment method you accept?
A: We accept bank transfer,western union, money gram,bitcoin, USDT,Credit card etc. and more bigger order we accept L/C at sight
Q3: Can i get tracking number after shipment ? and how long does the shipping take?
A: After shipment we will offer you tracking and tell you the website to track the package, usually the shipping time is 3-7days,but for some customers have no ability to declare customs, we use special line route to ship the package, it will take 10-12days to arrive,make sure 100% delivery
Q4: How can you guarantee the quality ?
A: All products we can supply you test report &you can also send our product to the third party to do test, if it is fake,we will full refund you.
Suppliers with verified business licenses
Audited Supplier 
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