Anti-inflammatory Raw Material CMS-121 CAS 1353224-53-9 with Bulk Price
| Product name |
CMS-121 |
| CAS number |
1353224-53-9 |
| Molecular formula |
C20H19NO3 |
| Molecular weight |
321.37 |
| Appearance |
White Powder |
| Purity |
99.0% |
| Packge |
1kg,5kg,10KG or under requirement |
| Description |
CMS-121 (CMS121) is a novel and potent fisetin-based derivative with anti-aging, neuroprotective, anti-inflammatory, antioxidative, and renoprotective activities. |
CMS121 is a substituted quin oline that has neuroprotective, anti-inflammatory, antioxidative, and renoprotective activities. It maintains glutathione (GSH) levels in HT22 mouse hippocampal cells in vitro in the presence of glutamate, induces differentiation of PC12 cells, prevents LPS-induced N9 microglial activation by 82% in N9 microglia, and scavenges free radicals in a Trolox equivalent activity concentration (TEAC) assay. CMS121 protects against ischemia and oxytosis in phenotypic screens in HT22 cells in vitro with EC50 values of 7 and 200 nM for preventing iodoacetic acid- or glutamate-induced cell death, respectively. It is also renoprotective, decreasing kidney weight loss and decreasing the expression of TNF-α, caspase-1, and inducible nit ric oxi de synthase (iNOS) in a SAMP8 mouse model of chronic kidney disease associated with rapid aging when administered at a dose of 10 mg/kg per day starting at nine months of age.
Our advantage:
We have PEPTIDES and S ARMS WAREHOUSE IN USA and Euro, you can receive order with 3 days without any customs problems.
We offer drop ship to your end clients in worldwide.
Why Choose us:
1). We have our own GMP lab .
2). Warehouses in USA and Euro to support your urgent need.
3). We can customize Peptides and Test Report HPLC and MS are available.
4). Western Union / Bank Transfer / Credit Card / Master Card / Bitcoin / T/T in Advance / LC @ SIGHT / Paypal for your option.
FAQ
Q1:Can i get free sample ?
A: Yes, most product we can send you small free sample, you just need to pay the shipping cost .
Q2:Which payment method you accept?
A: We accept bank transfer,western union, money gram,bitcoin, USDT,Credit card etc. and more bigger order we accept L/C at sight
Q3: Can i get tracking number after shipment ? and how long does the shipping take?
A: After shipment we will offer you tracking and tell you the website to track the package, usually the shipping time is 3-7days,but for some customers have no ability to declare customs, we use special line route to ship the package, it will take 10-12days to arrive,make sure 100% delivery
Q4: How can you guarantee the quality ?
A: All products we can supply you test report &you can also send our product to the third party to do test, if it is fake,we will full refund you.
Audited Supplier 
){kind=link}
){kind=link}