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WHAT IS THYMULIN?
Thymulin (also known as Thymic Factor, as Thymalin or under its old name Facteur Thymique Serique) is a nonapeptide produced by two distinct epithelial populations in the thymus first described by Bach in 1977. It requires zinc for biological activity.
Thymulin biological activity and antigenicity depend upon the presence of the metal zinc in the molecule. This pharmacologically active metallopeptide induces the differentiation of T-cells and enhances several functions of the various T-cell subsets in normal or partially thymus-deficient recipients. Its effect on suppressor T-cells is, so far, the most remarkable and should be the first to find useful clinical applications. The peptide is a natural hormone, available in synthetic form. It is not toxic and
one may foresee its clinical use as one of the major immunoregulatory agents in the near future.