Customization: | Available |
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CAS No.: | 76144-81-5 |
Formula: | C6h14n2o2 |
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Product name | Mildronate |
CAS No. | 76144-81-5 |
MF | C6H14N2O2 |
MW | 146.19 |
Melting point | 85-900C |
Boiling point | N/A |
Density | N/A |
Storage | Refrigerator |
3. Product Uses
In medicine, meld onium is principally used in the treatment of cardiac health issues. Doctors, particularly in Eastern Europe, use it to treat coronary heart disease. It is believed to help against angina and myocardial infarction, which many people know as heart attack.
Heart problems can give rise to ischemia. This is a condition where insufficient amounts of blood flow to organs in the body, including the heart. Meld onium supposedly helps to dilate blood vessels to improve the flow of blood and oxygen.
The drug alters pathways for carnitine through inhibition of the enzyme gamma-butyrobetaine dioxygenase (GBB). This reduces production of carnitine in the body, forcing the mitochondria to use glucose for energy generation. What this means is less oxidative stress and cellular damage than when reliance is on fatty acid beta oxidation.
It is believed Mildronate lowers the levels of N-oxide, a carnitine breakdown product thought to contribute to atherosclerosis and congestive heart failure. It supposedly promoted peripheral circulation and exercise capability in a 2005 study when combined with lisinopril, a substance which inhibits angiotensin converting enzymes.
The drug has been shown to be effective for treatment of acute ischemic stroke. It also appears to have anticonvulsants and antihypnotic benefits, making it potentially beneficial for seizure and alcohol intoxication treatments. Other conditions meld onium is used for include ocular ischemic syndrome and cerebral ischemia.
4. Product Side Effects
There is insufficient research on effects of Mildronate in humans. Most studies focused on animals and human trials are not of satisfactory standards to many experts. What this means is that not a lot can be said about adverse reactions.
However, some side effects that are thought possible from use include:
Some experts think that those using meld onium right now are somewhat putting themselves forward as guinea pigs. Other people will likely learn about the drug's safety, or lack of, from effects on such individuals.
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