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Product name |
Galantamine Hydrobromide |
CAS No. |
69353-21-5 |
Molecular Formula |
C17H22BrNO3 |
Molecular weight |
368.27 |
Grade Standard |
Medicine Grade |
Purity |
98% |
Galantamine is used for the treatment of mild to moderate Alzheimer's disease and various other
memory impairments, particularly those of vascular origin. It is an alkaloid that is obtained synthetically or from the bulbs and flowers of Galanthus Caucasicus (Caucasian snowdrop, Voronov's snowdrop), Galanthus woronowii (Amaryllidaceae) and related genera like Narcissus (daffodil)), Leucojum(snowflake) and Lycoris including Lycoris radiata (Red Spider Lily).
Galanthamine is natural extracted from lycoris radiate,is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE).it is used in the treatment of disorders of the central nerbous system and may be used as an antidote to nonpolarizing muscle relaxants.Galanthamine hydrobromide is a white to almost white powder; sparingly soluble in water
(1) Anti-cholinesterase .
(2) Stimulate and inhibit acetylcholinesterase, regulate intracephalic nicotine receptor position.
(3) Cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc.
(4) Improve the recognition function of light, mild Alzheimer disease patients significantly, and delay the process of function decrease of brain cells.
(5) Improve the conduction between nerve and muscle.