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Factory Price Bulk Supply High Purity Pharmaceutical API Canagliflozin CAS 842133-18-0
Name: Canagliflozin
English synonym: Canagliflozin(TA-7284)
CAS Number: 842133-18-0
Molecular formula: C24H25FO5S
Molecular weight: 444.52
EINECS No.: 695-192-1
Boiling point: 642.9±55.0 °C(Predicted)
Density: 1.364
Acidity coefficient (pKa): 13.34±0.70 (Predicted)
Canagliflozin is an SGLT2 inhibitor drug, an oral hypoglycemic drug targeting type 2 sodium-glucose cotransporter (SGLT2). SGLT-2 inhibitors have good prospects for the treatment of type 2 diabetes. The effectiveness and safety of the drug have been confirmed through existing clinical trials. Its single use or combined use with metformin and sulfonylureas can significantly reduce HbA1c and fasting blood glucose in patients with type 2 diabetes. The incidence of adverse reactions is similar to that of placebo, and the risk of hypoglycemia is lower, which can significantly reduce body weight.