Hair-Loss Peptide Ptd - dBm 95% Purity Senwayer Golden Product

• CAS No.: 300801-03-0
• Formula: C28h46cun12o8
• EINECS: 300801-03-0
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Technical
• Model NO.: PTD - DBM
• Colour: White
• Lead Time: 10-15days
• Transport Package: 1kg
• Specification: 99%
• Trademark: senwayer
• Origin: China
• Production Capacity: 10000kg/Month

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Product Description

Protein Transduction Domain-fused Dishevelled Binding Motif (PTD-DBM) is a man-made peptide which interacts with the mechanism of the hair loss linked endogenous protein, CXXC5, which is a negative feedback regulator of the Wnt/β-catenin pathway. Application of the peptide to bald laboratory mice resulted in new hair follicle growth.[1]

PTD-DBM is a peptide activating the Wnt/β-catenin signaling pathway functioning via interference of the binding of CXXC5 to Dishevelled (Dvl), an upstream component of the Wnt/β-catenin pathway. By topical application, the PTD-DBM promotes the formation of new hair follicles and prevents hair loss. Combinatory treatment of PTD-DBM with valproic acid (VPA), the activator of Wnt/β-catenin pathway, further induce hair re-growth as well as wound-induced hair neogenesis (WIHN).[2][1] The increased expression of CXXC5 in the bald scalps and excellent effects of PTD-DBM on hair growth in mice raised hopes for the application of this peptide on hair growth in the clinic.

 

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