USP Grade Raw Materials Polyvinylpyrrolidone CAS 9003-39-8 K30 PVP
| Product name |
Polyvinylpyrrolidone |
| CAS number |
9003-39-8 |
| Molecular formula |
CH4 |
| Molecular weight |
16.04246 |
| Appearance |
White Powder |
| Purity |
99.0% |
| Packge |
1kg,5kg,10KG or under requirement |
| Description |
PVP or povidone is a hygroscopic, amorphous, synthetic polymer consisting of linear 1-vinyl-2-pyrrolidinone groups. As a binder, PVP is used in the concentration range of 0.5%-5% w/w. Different degrees of polymerization of PVP resulted in polymers of various molecular weights. It is generally characterized by its viscosity in aqueous solution relative to that of water and expressed as a K value in the range of 10-120. |
The PVP was used as a blood plasma expander for trauma victims. It is used as a binder in many pharmaceutical tablets and it simply passes through the body when it is administered orally [89]. However, autopsies have found that crospovidone does contribute to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption [90]. PVP added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps, and surgical scrubs. It is known under the trade name Betadine and Pyodine. It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone-iodine is equally effective and safe as talc and may be preferred because of easy availability and low cost [91]. It is used as an aid for increasing the solubility of drugs in liquid and semiliquid dosage forms (syrups and soft gelatin capsules) and as an inhibitor of recrystallization.
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