High Purity Raw Material Peptide Pnc-27 Raw Powder

• Customization: Available
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Model NO.: Peptide Pnc-27 Raw Powder
• Quality: Refined
• Colour: White
• Types: Lyophilized Powder
• Storage: 2-8 Degree
• COA: Please Contact Senwayer Freely
• Grade Standard: Medcine Grade
• Transport Package: Foil Bag or 10 Vials Per Box
• Specification: 10mg/vial, 10 vials per box
• Trademark: Senwayer
• Origin: China
• Production Capacity: 5000 Box/Month

Product Description

We can provide lyophilized powder or raw powder for you, and the above is the price of lyophilized powder. If you have interestes in raw powder, you can contact me(Wicker: Andy1226) for the price of the raw powder.

Physical Characters and specifications

Product name	PNC-27
Other name	N/A
Appearance	White powder
Purity	95%MIN (HPLC)
Package	100mg, 1g
Grade	Cosmetic grade

For scientific research use only. Not for human consumption.

If need FITC free, please contact with us before payment.

Name: PNC-27
Sequence:  PPLSQETFSDLWKLL
Molecular formula: C84H128N18O24
Molecular weight: 1772.93
Purity:  95.0% min
Source :  synthetic

Storage
Stored in a freezer at or below -9C.
After reconstitution, peptide should be kept refrigerated.


Product description

PNC-27 is a membrane-active peptide that binds to the HDM-2 protein expressed in the cancer cell membranes of solid tissue tumor cells and induces transmembrane pore formation in cancer, but not in normal cells, resulting in tumor cell necrosis that is independent of p53 activity in these cells. 

PNC-27 is a peptide that contains p53 protein amino acid residues 12-26 of its HDM-2 binding domain attached to a transmembrane-penetrating sequence, also called the membrane residency peptide (MRP). Both PNC-27 and PNC-28 (which has a sequence that is identical to that of PNC-27 but lacks the first six amino acid residues of PNC-27 (i.e., p53 residues 17-26) are lethal to a wide variety of cancer cells with IC50 values ranging from around 75 ug/ml (18.6 uM) to 200 ug/ml (50 uM). On the other hand, neither peptide affects normal or untransformed cells in culture, including human hematopoietic stem cells even at the highest doses (around 500 ug/ml) tested. The latter finding suggests that both peptides would not be toxic to bone marrow function in contrast to the effects of many chemotherapeutic agents.
 

 

 

 

Contact for more product and  We also supply 
Related products:

 

No.	Product Name	CAS No.
Anti-wrinkle & Anti-aging Series
1	Acetyl Hexapeptide-8	616204-22-9
2	Acetyl Octapeptide-3/Snap-8	868844-74-0
3	Palmitoyl Tripeptide-5  /Collagen Peptide	623172-56-5
4	Palmitoyl Pentapeptide-4 /Matrixyl Acetate	214047-00-4
5	Pentapeptide-18 /Leuphasyl	64963-01-5
6	Hexapeptide-10/Serilesine	146439-94-3
7	Palmitoyl Hexapeptide / Lipopeptide Acetate	171263-26-6
8	Palmitoyl Tripeptide-1	147732-56-7
9	Pentapeptide-3/Vialox Peptide	135679-88-8
10	Acetyl Tetrapeptide-2	757942-88-4
11	Acetyl Tetrapeptide-9	928006-50-2
12	L-Carnosine	305-84-0
13	Decorinyl/Tripeptide-10 Citrulline	960531-53-7
14	Palmitoyl Tripeptide-38	1447824-23-8
15	Acetyl Decapeptide-3	935288-50-9
16	Hexapeptide-11	--------
Whitening & Freckle Removing Series
1	Nonapeptide-1/Melitane	158563-45-2
2	Tetrapeptide-30	---------
3	Decapeptide-12	---------
4	Hexapeptide-2	---------
5	Melanostatin DM	123689-72-5
6	Oligopeptide-68	1206525-47-4
Eye Care and Hair Growth Series
1	Acetyl Tetrapeptide-5	820959-17-9
2	Myristoyl Pentapeptide-17	959610-30-1
3	Myristoyl Tetrapeptide-12	959610-24-3
4	Acetyl Tetrapeptide-3/Capixyl	155149-79-4
5	Biotinoyl Tripeptide-1	299157-54-3
6	Melitane/Acetyl Hexapeptide-1	448944-47-6
7	Myristoyl Pentapeptide-4	---------
Anti-allergic & Skin Repair Series
1	Pal-Tetrapeptide-7 /Pal-Tetrapeptide-3	221227-05-0
2	Copper Peptide	49557-75-7
3	Hexapeptide-9	1228371-11-6
4	Palmitoyl Tripeptide-8	936544-53-5
5	Oligopeptide-10	---------
6	LZ1 Peptide	---------
Breast Series
1	Acetyl Hexapeptide-38	1400634-44-7
Weight Loss series
1	Acetyl Hexapeptide-39	---------

 

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Customized Service

 

FAQ

Q1:Can i get free sample ?
A: Yes, most product we can send you small free sample, you just need to pay the shipping cost .
 

Q2:Which payment method you accept?
A: We accept bank transfer,western union, money gram,bitcoin, USDT,Credit card etc. and more bigger order we accept L/C at sight
 

Q3: Can i get tracking number after shipment ? and how long does the shipping take?
A: After shipment we will offer you tracking and tell you the website to track the package, usually the shipping time is 3-7days,but for some customers have no ability to declare customs, we use special line route to ship the package, it will take 10-12days to arrive,make sure 100% delivery
 

Q4: How can you guarantee the quality ?
A: All products we can supply you test report &you can also send our product to the third party to do test, if it is fake,we will full refund you.