Customization: | Available |
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Powder: | Yes |
Customized: | Non-Customized |
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Product name | IDRA21 |
CAS number | 22503-72-6 |
Molecular formula | C8H9ClN2O2S |
Molecular weight | 232.69 |
Melting point | 209 °C(Solv: acetic acid |
Boiling point | 405.1±55.0 °C(Predicted) |
Density | 1.394±0.06 g/cm3(Predicted) |
Appearance | White Powder |
Purity | 99.0% |
Function | 1.Idra-21 can Increases in cognition 2.Idra-21 can Increased Task Accuracy 3.Idra-21 can Increases in Short Term Memory 4.Idra-21 can Potential Therapeutic Effects On Depression 5.Idra-21 can Neuroprotection 6.Idra-21 can Potential Therapeutic Effects On Schizophrenia |
Discribe | IDRA-21 is a positive allosteric modulator (PAM) of the AMPA receptor and a benzothiadiazine derivative. It is a chiral molecule, with (+)-IDRA-21 being the active form. IDRA-21 shows nootropic effects in animal studies, significantly improving learning and memory. It is around 10-30 times more potent than aniracetam in reversing cognitive deficits induced by scopolamine, and produces sustained effects lasting for up to 48 hours after a single dose. The mechanism for this action is thought to be through promoting the induction of long-term potentiation between synapses in the brain. |