| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Product name |
Telmisartan |
|
CAS No. |
144701-48-4 |
| Molecular Formula | C33H30N4O2 |
| Molecular Weight | 514.63 |
| Purity | 99% |
Telmisartan is an angiotensin II receptor used to treat hypertension. Most blood pressure lowering drugs currently have a maximum effect of 10 hours. Telmisartan is the most powerful drug of its kind. Clinical studies have shown that Telmisartan can reduce blood pressure 24 hours a day, including early morning, when cardiovascular disease is at its highest risk. Telmisartan (Telmisartan) is also currently the only one kind of angiotensin receptor blockers, confirmed by clinical research in addition to high blood pressure in patients with cardiovascular risk and diabetes patients, can provide additional cardiovascular protection, reduce their death due to cardiovascular disease, myocardial infarction, or stroke.
Telmisartan is an angiotensin II receptor blocker (ARB) that has high affinity for the angiotensin II receptor type 1 (AT1).
Telmisartan interferes with the binding of angiotensin II to AT1 receptors in vascular smooth muscle and thus inhibits the vasoconstricting action of angiotensin II. Additionally, telmisartan is a selective modulator of peroxisome proliferator-activated receptor gamma (PPARγ), an essential regulator of glucose metabolism. Therefore, telmisartan is useful for studying hypertension.
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