Powder: | Yes |
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Customized: | Non-Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | Solid |
Purity: | >99% |
Samples: |
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Customization: |
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Name: Dutasteride
English synonyms: 5,6-Dehydro-17&alpha
CAS Number: 164656-23-9
Molecular formula: C27H30F6N2O2
Molecular weight: 528.53
EINECS number: 638-758-5
Melting point: 242-250°C
Boiling point: 620.3±55.0°C(Predicted)
Density: 1.303±0.06g/cm3(Predicted)
Storage conditions: -20°C
Solubility: DMSO: soluble2mg/mL, clear
Acidity coefficient (pKa): 13.32±0.70 (Predicted)
Form: powder
Color: white to beige
Optical activity: [α]/D+18to+24°,c=1inchloroform-d
Dutasteride is a new dual inhibitor of 5α reductase, which can inhibit both 5α reductase-1 and 5α reductase-2. It can reduce the concentration of DHT more than finasteride (94.7% vs. 70.8%). The inhibitory effect of dutasteride on 5α reductase-1 is 60 times that of finasteride. 27 months after taking dutasteride, the incidence of prostate cancer was 50% lower than that of the placebo group.
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