Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity

• CAS No.: 40077-57-4
• Formula: C147h238n44o42s
• EINECS: 40077-57-4
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Technical
• Model NO.: Livagen
• Colour: White
• Lead Time: 10-15days
• Transport Package: 1kg
• Specification: 99%
• Trademark: senwayer
• Origin: China
• Production Capacity: 10000kg/Month

Product Description

    

Product Description

The effect of new peptide bioregulators--Livagen (Lys-Glu-Asp-Ala) and Epitalon (Ala-Glu-Asp-Gly)--on endogenous opioid system was studied, particularly, their ability to change the activity of enkephalin-degrading enzymes from serum and interact with opioid receptors of the brain membrane fraction. Enkephalinase activity was assayed in vitro by the rate of 3H-Leu-enkephalin hydrolysis in the presence of the tested peptides. Livagen and Epitalon inhibited enkephalin-degrading enzymes from human serum. Livagen proved to be more efficient also as compared to well-known peptidase inhibitors such as puromycin, leupeptin, and D-PAM. The dose-inhibitory effect curves for Livagen and Epitalon were plotted; their IC50 equaled 20 and 500 microM, respectively. The interaction between the peptides and opioid receptors was estimated using a radioreceptor method with [3H][D-Ala2, D-Leu5]-enkephalin. No interaction was observed between the tested peptides and mu- or delta-opioid receptors of the membrane fraction from the rat brain.
 

Detailed Photos

 

Certifications

Packaging & Shipping

Company Profile

 

Our Advantages

 

FAQ